Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313625 | 0.80 | MAPT (0.40) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL15660988 | 0.79 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL15660991 | 0.79 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL15660986 | 0.79 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL21160712 | 0.79 | TTR (0.43) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL21037023 | 0.78 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL11930608 | 0.73 | RAB9A (0.52) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL14518023 | 0.72 | MAPT (0.58) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL29805838 | 0.71 | XDH (0.49) | MAPTKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL4464221 | 0.71 | XDH (0.49) | MAPTKDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-08-08 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | MAPT 2624/4885KDM4E 4671/4885MEN1 2099/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | MAPT 3407/4885KDM4E 4770/4885MEN1 1100/4885 |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | DNASE1, POLRMT, DCLRE1B | MAPT 2048/4885KDM4E 3930/4885MEN1 3709/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | MAPT 2624/4885KDM4E 4671/4885MEN1 2099/4885 |
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | DNASE1, POLRMT, DCLRE1B | MAPT 2048/4885KDM4E 3930/4885MEN1 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.