Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 12/20 | 0.41 |
| ▸ | NOS1 | P29475 | 12/20 | 0.41 |
| ▸ | NOS2 | P35228 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160476 | 0.80 | EGFR (0.45) | ALDH1A1HPGD | |
| SCHEMBL24991972 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL29100113 | 0.76 | ALDH1A1 (0.62) | NOS3NOS1NOS2ALDH1A1MEN1 | |
| SCHEMBL7528285 | 0.74 | MAPT (0.50) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL21036846 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL18902663 | 0.70 | MEN1 (0.51) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL15652707 | 0.70 | ALDH1A1 (0.41) | NOS3NOS1NOS2ALDH1A1MEN1 | |
| SCHEMBL22295812 | 0.70 | NOS3 (0.34) | NOS3NOS1NOS2ALDH1A1MEN1 | |
| SCHEMBL21160621 | 0.69 | MAPT (0.51) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL14265691 | 0.69 | MAPT (0.43) | ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | NOS3 4214/4885NOS1 4212/4885NOS2 4370/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | NOS3 4214/4885NOS1 4212/4885NOS2 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.