Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | MAP3K12 | Q12852 | 14/20 | 0.42 |
| ▸ | DLK1 | P80370 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018943 | 0.86 | MAP3K12 (0.43) | HRH3MAP3K12DLK1CHRM2HTR1A | |
| SCHEMBL21037498 | 0.84 | MAP3K12 (0.55) | MAP3K12ADRB1 | |
| SCHEMBL2338512 | 0.82 | NOS3 (0.50) | MAP3K12ADRB1 | |
| SCHEMBL18965273 | 0.79 | HRH3 (0.47) | HRH3OGA | |
| SCHEMBL28284245 | 0.79 | NOS3 (0.47) | MAP3K12ADRB1 | |
| SCHEMBL28282678 | 0.77 | NOS3 (0.46) | TLR8MAP3K12ADRB1 | |
| SCHEMBL13063398 | 0.75 | MAP3K12 (0.45) | MAP3K12DLK1ADRB1 | |
| SCHEMBL7074219 | 0.75 | MAPK1 (0.58) | MAP3K12DLK1ADRB1 | |
| SCHEMBL13018936 | 0.74 | HRH3 (0.65) | HRH3TLR9TLR8TLR7ADRB1 | |
| SCHEMBL10057681 | 0.74 | DRD2 (0.63) | HRH3CHRM2HTR1ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161499-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161499-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | ACHE, AADAC, ATL3 | HRH3 1945/4885TLR9 4259/4885TLR8 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.