Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552220 | 0.85 | ALOX5 (0.50) | ALOX5HDAC8SLC6A4SLC6A3MAPT | |
| SCHEMBL21102259 | 0.81 | ALOX5 (0.48) | ALOX5HDAC8SLC6A4SLC6A3GGPS1 | |
| SCHEMBL19200773 | 0.81 | HDAC8 (0.50) | ALOX5HDAC8MAPTTHRBL3MBTL1 | |
| SCHEMBL18165288 | 0.81 | HDAC8 (0.50) | ALOX5HDAC8SLC6A3MAPTNR4A2 | |
| SCHEMBL21102641 | 0.80 | SLC6A3 (0.48) | ALOX5HDAC8SLC6A3GGPS1TNKS | |
| SCHEMBL4554338 | 0.80 | ALOX5 (0.50) | ALOX5HDAC8SLC6A4SLC6A3MAPT | |
| SCHEMBL21102389 | 0.80 | HDAC8 (0.49) | ALOX5HDAC8SLC6A3MAPTATM | |
| SCHEMBL18357017 | 0.79 | HDAC8 (0.47) | ALOX5HDAC8MAPTTHRBNR4A2 | |
| SCHEMBL16745227 | 0.77 | SLC6A4 (0.48) | ALOX5HDAC8SLC6A4SLC6A3MAPT | |
| SCHEMBL21037808 | 0.77 | SLC6A3 (0.52) | SLC6A4SLC6A3MAPTSLC6A2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11832513-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2023-11-28 | — | — | US | disclosed |
| US-11832513-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2023-11-28 | — | — | US | disclosed |
| EP-4242286-A2 | MATERIALS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2023-09-13 | — | — | EP | disclosed |
| EP-3714022-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-20200303654-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| WO-2019101719-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11832513-B2 | Materials for electronic devices | PNMT, DDT, COMT | ALOX5 2153/4885HDAC8 4729/4885SLC6A4 355/4885 |
| US-20200303654-A1 | MATERIALS FOR ELECTRONIC DEVICES | PNMT, DDT, COMT | ALOX5 2153/4885HDAC8 4729/4885SLC6A4 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.