SCHEMBL21037852

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30805716	1.00	PDK2 (0.49)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL19850003	0.96	PDK2 (0.51)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL30805727	0.96	PDK2 (0.47)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL29575912	0.96	PDK2 (0.51)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL22920879	0.93	MEN1 (0.50)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL21924841	0.90	PDK2 (0.53)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL19147675	0.89	PDK2 (0.58)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL22150986	0.89	MEN1 (0.46)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL23382970	0.88	S100A4 (0.47)	PDK2MEN1KMT2AMAPTKDM4E
	SCHEMBL17816711	0.87	PDK2 (0.56)	PDK2MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.