SCHEMBL21039282

SCHEMBL21039282

c1ccc(-c2ccc3c(c2)oc2cc(N(c4ccccc4)c4cccc(C5(c6ccccc6)c6ccccc6-c6ccccc65)c4)ccc23)cc1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21039290 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21039284 0.95 MEN1 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21039286 0.95 MEN1 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL22134217 0.94 AHR (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22403659 0.94 AHR (0.32) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22403541 0.94 AHR (0.32) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22403479 0.94 AHR (0.32) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22403540 0.92 AHR (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22036282 0.92 AHR (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL17827459 0.92 MMP12 (0.33) PDK2MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793068-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-11793068-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-20210359230-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-18 US disclosed
US-11121329-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-09-14 US disclosed
US-20190165285-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210359230-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME AOC2, H1-2, CHRM1 PDK2 2276/4885MEN1 1998/4885KMT2A 329/4885
US-11121329-B2 Amine compound and organic electroluminescence device including the same AOC2, H1-2, CHRM1 PDK2 2276/4885MEN1 1998/4885KMT2A 329/4885
US-20190165285-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME ODC1, PNMT, SAT1 PDK2 1854/4885MEN1 195/4885KMT2A 234/4885
US-11793068-B2 Amine compound and organic electroluminescence device including the same AOC2, H1-2, CHRM1 PDK2 2276/4885MEN1 1998/4885KMT2A 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.