Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539161 | 0.90 | RARA (0.54) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL15538196 | 0.87 | SSTR5 (0.43) | SSTR5KCNH2RARARARB | |
| SCHEMBL15539858 | 0.85 | SSTR5 (0.55) | SSTR5KCNH2RARBPARP15PARP10 | |
| SCHEMBL16758080 | 0.83 | SSTR5 (0.43) | SSTR5KCNH2 | |
| SCHEMBL15538034 | 0.81 | CHRM2 (0.44) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL15539206 | 0.81 | GPR119 (0.57) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL15538771 | 0.81 | GPR119 (0.45) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL16757956 | 0.80 | RARB (0.44) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL18842727 | 0.80 | RARA (0.51) | SSTR5KCNH2RARARARBCHRM2 | |
| SCHEMBL15538445 | 0.80 | RARA (0.51) | SSTR5KCNH2RARARARBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |