Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.53 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.53 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043805 | 0.92 | ERCC1 (0.51) | ERCC1ERCC4HDAC1HDAC8HDAC6 | |
| SCHEMBL21043821 | 0.90 | ATAD2 (0.43) | ERCC1ERCC4ATAD2HDAC1HDAC8 | |
| SCHEMBL21043836 | 0.90 | HDAC1 (0.45) | ERCC1ERCC4ATAD2HDAC1HDAC8 | |
| SCHEMBL21043857 | 0.89 | ATAD2 (0.49) | ATAD2HDAC1HDAC8HDAC6POLB | |
| SCHEMBL21043787 | 0.83 | HDAC1 (0.44) | ERCC1ERCC4ATAD2HDAC1HDAC8 | |
| SCHEMBL21043841 | 0.83 | P2RX7 (0.42) | ERCC1ERCC4HDAC1HDAC8HDAC6 | |
| SCHEMBL21043852 | 0.82 | ATAD2 (0.45) | ATAD2HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL21043839 | 0.82 | ATAD2 (0.45) | ATAD2HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL21043804 | 0.81 | ATAD2 (0.50) | ATAD2HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL21043880 | 0.81 | ATAD2 (0.50) | ATAD2HDAC1HDAC8HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |