Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CBX7 | O95931 | 1/20 | 0.35 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043836 | 0.93 | HDAC1 (0.45) | HDAC1HDAC8HDAC6ERCC1ERCC4 | |
| SCHEMBL21043805 | 0.91 | ERCC1 (0.51) | HDAC1HDAC8HDAC6ERCC1ERCC4 | |
| SCHEMBL21043871 | 0.89 | HDAC6 (0.40) | HDAC1HDAC8HDAC6POLBDRD2 | |
| SCHEMBL21043813 | 0.88 | HDAC1 (0.42) | HDAC1HDAC8HDAC6POLBDRD2 | |
| SCHEMBL21043856 | 0.87 | GAA (0.49) | HDAC1HDAC8HDAC6NPY5RGAA | |
| SCHEMBL21043822 | 0.83 | HDAC1 (0.44) | HDAC1HDAC8HDAC6GAAL3MBTL1 | |
| SCHEMBL21043841 | 0.83 | P2RX7 (0.42) | HDAC1HDAC8HDAC6ERCC1ERCC4 | |
| SCHEMBL21043873 | 0.83 | HDAC1 (0.42) | HDAC1HDAC8HDAC6POLBDRD2 | |
| SCHEMBL21043769 | 0.83 | ERCC1 (0.53) | HDAC1HDAC8HDAC6ERCC1ERCC4 | |
| SCHEMBL21043798 | 0.81 | ATAD2 (0.43) | HDAC1HDAC8HDAC6POLBATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |