Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043794 | 0.89 | BRD4 (0.53) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043815 | 0.86 | POLB (0.48) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043843 | 0.83 | TP53 (0.61) | POLBTP53LMNACYP2C9CYP2C19 | |
| SCHEMBL21043849 | 0.83 | MEN1 (0.49) | POLBTP53LMNAMEN1KMT2A | |
| SCHEMBL21043845 | 0.81 | BRD4 (0.53) | POLBTP53LMNACYP1A2HDAC1 | |
| SCHEMBL21043777 | 0.81 | LMNA (0.50) | POLBTP53LMNAMEN1KMT2A | |
| SCHEMBL21043801 | 0.80 | POLB (0.45) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL19865932 | 0.80 | HDAC1 (0.46) | POLBTP53LMNAMEN1KMT2A | |
| SCHEMBL21043856 | 0.80 | GAA (0.49) | POLBMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL21043855 | 0.80 | MAPT (0.52) | POLBTP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |