Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043854 | 0.92 | POLB (0.50) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043774 | 0.86 | POLB (0.63) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043849 | 0.83 | MEN1 (0.49) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043801 | 0.82 | POLB (0.45) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043794 | 0.81 | BRD4 (0.53) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043781 | 0.81 | POLB (0.46) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043847 | 0.81 | POLB (0.44) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL19857236 | 0.81 | MAPT (0.46) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043878 | 0.81 | CYP19A1 (0.48) | POLBTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043777 | 0.81 | LMNA (0.50) | POLBTP53LMNAHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |