Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043855 | 0.91 | MAPT (0.52) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL21043867 | 0.90 | POLB (0.59) | POLBTP53MAPTCYP19A1LMNA | |
| SCHEMBL21043878 | 0.90 | CYP19A1 (0.48) | KMT2APOLBTP53MAPTCYP19A1 | |
| SCHEMBL21043777 | 0.89 | LMNA (0.50) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL21043856 | 0.88 | GAA (0.49) | MEN1KMT2APOLBHDAC1HDAC8 | |
| SCHEMBL21043784 | 0.88 | CYP19A1 (0.52) | POLBTP53MAPTCYP19A1LMNA | |
| SCHEMBL21043782 | 0.88 | CYP19A1 (0.52) | MEN1KMT2APOLBMAPTCYP19A1 | |
| SCHEMBL21043838 | 0.85 | TP53 (0.47) | POLBTP53MAPTLMNAALDH1A1 | |
| SCHEMBL21043806 | 0.85 | CYP19A1 (0.52) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL21043844 | 0.84 | THRB (0.43) | POLBTP53MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |