Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043781 | 0.89 | POLB (0.46) | MAPTPOLBLMNAHDAC1HDAC8 | |
| SCHEMBL21043850 | 0.87 | HDAC1 (0.40) | POLBLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL21043867 | 0.84 | POLB (0.59) | MAPTPOLBLMNATP53 | |
| SCHEMBL21043778 | 0.84 | HDAC1 (0.39) | POLBLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL21043777 | 0.84 | LMNA (0.50) | MAPTPOLBLMNAHDAC1HDAC8 | |
| SCHEMBL21043796 | 0.84 | POLB (0.45) | MAPTPOLBLMNAHDAC1HDAC8 | |
| SCHEMBL21043807 | 0.84 | CHRM1 (0.40) | POLBLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL21043834 | 0.82 | CES2 (0.45) | POLBLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL21043801 | 0.82 | POLB (0.45) | MAPTPOLBLMNAHDAC1HDAC8 | |
| SCHEMBL19865932 | 0.82 | HDAC1 (0.46) | MAPTPOLBLMNAHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127319-A1 | PLANT GROWTH REGULATOR COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | claimed |
| WO-2020127319-A1 | PLANT GROWTH REGULATOR COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |