Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043790 | 0.92 | POLB (0.61) | POLBLMNAUSP2CYP19A1TP53 | |
| SCHEMBL21043855 | 0.91 | MAPT (0.52) | POLBLMNACYP19A1TP53MAPT | |
| SCHEMBL21043784 | 0.90 | CYP19A1 (0.52) | POLBLMNACYP19A1TP53MAPT | |
| SCHEMBL21043878 | 0.90 | CYP19A1 (0.48) | POLBLMNACYP19A1TP53MAPT | |
| SCHEMBL21043849 | 0.90 | MEN1 (0.49) | POLBLMNACYP19A1TP53MAPT | |
| SCHEMBL21043777 | 0.89 | LMNA (0.50) | POLBLMNATP53MAPTTHRB | |
| SCHEMBL21043782 | 0.88 | CYP19A1 (0.52) | POLBLMNAUSP2CYP19A1MAPT | |
| SCHEMBL21043796 | 0.87 | POLB (0.45) | POLBLMNAMAPTTHRB | |
| SCHEMBL21043806 | 0.85 | CYP19A1 (0.52) | POLBLMNACYP19A1TP53MAPT | |
| SCHEMBL21043824 | 0.84 | MAPT (0.43) | POLBLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127319-A1 | PLANT GROWTH REGULATOR COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | claimed |
| WO-2020127319-A1 | PLANT GROWTH REGULATOR COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |