Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043826 | 0.92 | ATAD2 (0.46) | POLBRXFP1TP53HDAC1HDAC8 | |
| SCHEMBL21043801 | 0.89 | POLB (0.45) | POLBRXFP1TP53HDAC1HDAC8 | |
| SCHEMBL21043781 | 0.88 | POLB (0.46) | POLBRXFP1TP53HDAC1HDAC8 | |
| SCHEMBL21043791 | 0.86 | NPY5R (0.44) | POLBRXFP1TP53HDAC1HDAC8 | |
| SCHEMBL21043777 | 0.85 | LMNA (0.50) | POLBTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL21043813 | 0.85 | HDAC1 (0.42) | POLBRXFP1TP53HDAC1HDAC8 | |
| SCHEMBL21043878 | 0.84 | CYP19A1 (0.48) | POLBTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL19857236 | 0.82 | MAPT (0.46) | POLBTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL21043816 | 0.81 | CHRM1 (0.43) | POLBHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL19865932 | 0.81 | HDAC1 (0.46) | POLBTP53HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |