Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043859 | 0.92 | MAPT (0.48) | MAPTTP53POLBATMLMNA | |
| SCHEMBL21043801 | 0.89 | POLB (0.45) | MAPTTP53POLBLMNAHDAC1 | |
| SCHEMBL21043855 | 0.87 | MAPT (0.52) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL21043820 | 0.83 | HDAC1 (0.43) | MAPTTP53LMNAHDAC1HDAC8 | |
| SCHEMBL21043796 | 0.83 | POLB (0.45) | MAPTPOLBLMNAHDAC1HDAC8 | |
| SCHEMBL21043781 | 0.82 | POLB (0.46) | MAPTTP53POLBLMNAHDAC1 | |
| SCHEMBL21043847 | 0.82 | POLB (0.44) | MAPTTP53POLBLMNAHDAC1 | |
| SCHEMBL21043777 | 0.81 | LMNA (0.50) | MAPTTP53POLBLMNAHDAC1 | |
| SCHEMBL21074416 | 0.81 | KMT2A (0.44) | MAPTTP53POLBATMLMNA | |
| SCHEMBL21043815 | 0.81 | POLB (0.48) | MAPTTP53POLBLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207440-B | 2-oxo-3, 4-dihydroquinoline compounds as plant growth regulators | 先正达参股股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-27 | — | — | US | disclosed |
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | CDC25B, OSR1, CDC25C | MAPT 4499/4885TP53 2837/4885POLB 2572/4885 |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | CDC25B, OSR1, CDC25C | MAPT 4499/4885TP53 2837/4885POLB 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.