Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857236 | 0.92 | MAPT (0.46) | MAPTPOLBATMTP53LMNA | |
| SCHEMBL21043786 | 0.88 | ATAD2 (0.47) | MAPTATAD2POLBTP53LMNA | |
| SCHEMBL21043802 | 0.86 | MAPT (0.53) | MAPTATAD2POLBATMTP53 | |
| SCHEMBL21074416 | 0.83 | KMT2A (0.44) | MAPTPOLBATMTP53LMNA | |
| SCHEMBL21043804 | 0.83 | ATAD2 (0.50) | MAPTATAD2TP53LMNAALDH1A1 | |
| SCHEMBL21043848 | 0.82 | POLB (0.46) | MAPTATAD2POLBLMNA | |
| SCHEMBL21043832 | 0.81 | POLB (0.48) | MAPTATAD2POLBTP53LMNA | |
| SCHEMBL21043826 | 0.81 | ATAD2 (0.46) | MAPTATAD2POLBTP53LMNA | |
| SCHEMBL21043862 | 0.81 | LMNA (0.52) | MAPTATAD2POLBTP53LMNA | |
| SCHEMBL21043801 | 0.80 | POLB (0.45) | MAPTATAD2POLBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |