Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.53 |
| ▸ | USP7 | Q93009 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044264 | 0.81 | CYP11B2 (0.57) | MAP4K4CYP11B2CYP11B1USP7PIK3CG | |
| SCHEMBL30725703 | 0.81 | CYP11B2 (0.57) | MAP4K4CYP11B2CYP11B1USP7PIK3CG | |
| SCHEMBL15156799 | 0.80 | PIK3CD (0.59) | PIK3CDMAP4K4CYP11B2CYP1A2KCNH2 | |
| SCHEMBL5562910 | 0.80 | MAP4K4 (0.62) | PIK3CDMAP4K4CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL2983844 | 0.80 | CYP11B2 (0.61) | MAP4K4CYP11B2CYP11B1PIK3CGPRMT5 | |
| SCHEMBL17116617 | 0.78 | CYP11B2 (0.62) | MAP4K4CYP11B2CYP11B1PIK3CGPRMT5 | |
| SCHEMBL17116663 | 0.77 | CYP11B1 (0.49) | MAP4K4CYP11B2CYP11B1USP7PRMT5 | |
| SCHEMBL18223993 | 0.76 | CYP11B2 (0.52) | PIK3CDMAP4K4CYP11B2CYP11B1PIK3CG | |
| SCHEMBL17116680 | 0.76 | CYP11B2 (0.58) | MAP4K4CYP11B2CYP11B1PIK3CGPRMT5 | |
| SCHEMBL21044254 | 0.74 | CYP11B2 (0.70) | MAP4K4CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717459-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2023-05-23 | — | — | US | disclosed |
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2023-05-23 | — | — | US | disclosed |
| US-20210002269-A1 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-01-07 | — | — | US | disclosed |
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | PIK3CD 2075/4885MAP4K4 1996/4885CYP11B2 1869/4885 |
| US-20210002269-A1 | COMPOUNDS | UGT1A1, CYP1A1, CYP19A1 | PIK3CD 3859/4885MAP4K4 3209/4885CYP11B2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.