Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044282 | 0.88 | ALDH1A1 (0.39) | HTT | |
| SCHEMBL21044365 | 0.88 | HCAR3 (0.34) | TSHR | |
| SCHEMBL21044304 | 0.85 | SRD5A2 (0.34) | HTTGRIA2GRIA4 | |
| SCHEMBL21044578 | 0.85 | CA1 (0.36) | TSHRHTTGRIA2GRIA4 | |
| SCHEMBL21044302 | 0.84 | GRIA2 (0.36) | HTTGRIA2GRIA4 | |
| SCHEMBL21044572 | 0.81 | HCAR3 (0.35) | — | |
| SCHEMBL21044397 | 0.80 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL21044362 | 0.79 | PTGDR (0.38) | TSHRHTT | |
| SCHEMBL21044478 | 0.74 | HCAR2 (0.34) | — | |
| SCHEMBL21044535 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |