Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044365 | 0.84 | HCAR3 (0.34) | HCAR3HCAR2 | |
| SCHEMBL21044282 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL21044208 | 0.81 | THRB (0.32) | — | |
| SCHEMBL21044578 | 0.79 | CA1 (0.36) | — | |
| SCHEMBL21044304 | 0.79 | SRD5A2 (0.34) | — | |
| SCHEMBL21044478 | 0.79 | HCAR2 (0.34) | HCAR2SLC6A2SLC6A4DAO | |
| SCHEMBL21044302 | 0.78 | GRIA2 (0.36) | — | |
| SCHEMBL21044522 | 0.73 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL21044535 | 0.71 | — | — | |
| SCHEMBL21044576 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |