Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455734 | 0.75 | DHFR (0.53) | KDM4EHPGDALDH1A1DHFRKMT2A | |
| SCHEMBL27532000 | 0.73 | TTR (0.56) | KDM4EHPGDALDH1A1DHFRKMT2A | |
| SCHEMBL28044056 | 0.73 | MYC (0.65) | KDM4EHPGDALDH1A1DHFRKMT2A | |
| SCHEMBL10644853 | 0.73 | PIN1 (0.63) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9124028 | 0.71 | WDR5 (0.79) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL29458346 | 0.71 | WDR5 (0.79) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| Bicarbonate SCHEMBL11569280 | 0.71 | NR4A1 (0.58) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| Acetic Acid SCHEMBL29253717 | 0.70 | MCL1 (0.54) | KDM4EHPGDALDH1A1DHFRKMT2A | |
| SCHEMBL27321151 | 0.70 | NR4A1 (0.58) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL6922777 | 0.70 | KDM4E (0.52) | KDM4EHPGDALDH1A1DHFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |