Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222214 | 0.79 | PTPN1 (0.46) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL218606 | 0.78 | LMNA (0.61) | PTPN1TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28116938 | 0.78 | NAPRT (0.61) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3432130 | 0.78 | NAPRT (0.61) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL2231066 | 0.78 | P2RX7 (0.59) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| Bromide SCHEMBL4126411 | 0.76 | NAPRT (0.59) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| Bromide SCHEMBL15753399 | 0.76 | P2RX7 (0.57) | PTPN1KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL2902900 | 0.76 | KDM4E (0.63) | KDM4ETDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL30863406 | 0.76 | KDM4E (0.63) | KDM4ETDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL15228399 | 0.75 | PARP1 (0.62) | PTPN1KDM4ETDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010906-B1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS | AB SCIENCE (FR) | 2019-06-12 | — | — | EP | disclosed |