Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 9/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626886 | 0.83 | PTK2 (0.37) | PTK2LRRK2 | |
| SCHEMBL17258736 | 0.82 | PTK2 (0.36) | PTK2SLC22A12LRRK2 | |
| SCHEMBL21048874 | 0.81 | KDM4E (0.36) | PTK2SLC22A12 | |
| SCHEMBL1230919 | 0.72 | PTK2 (0.50) | PTK2 | |
| Hydrochloric Acid SCHEMBL21048838 | 0.72 | JAK2 (0.37) | PTK2 | |
| SCHEMBL1628384 | 0.71 | PTK2 (0.39) | PTK2LRRK2 | |
| SCHEMBL21048809 | 0.69 | GAA (0.33) | SLC22A12LRRK2 | |
| SCHEMBL1625404 | 0.68 | PTK2 (0.38) | PTK2LRRK2 | |
| SCHEMBL13082590 | 0.68 | CHRNB2 (0.40) | SLC22A12 | |
| SCHEMBL1626116 | 0.66 | PTK2 (0.37) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |