Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17258830 | 0.84 | KDM4C (0.38) | RECQLKMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL17258675 | 0.78 | KDM4C (0.38) | KMT2AMEN1L3MBTL1LMNAGAA | |
| SCHEMBL28840926 | 0.73 | TP53 (0.48) | KMT2AMEN1TP53L3MBTL1 | |
| SCHEMBL21048978 | 0.72 | TP53 (0.52) | KMT2AMEN1TP53GAAALDH1A1 | |
| SCHEMBL31548465 | 0.67 | MEN1 (0.41) | KMT2AMEN1KDM4C | |
| SCHEMBL17258976 | 0.67 | TP53 (0.42) | KMT2AMEN1TP53 | |
| SCHEMBL17258893 | 0.67 | ALDH1A1 (0.53) | KMT2AMEN1TP53L3MBTL1GAA | |
| SCHEMBL20857107 | 0.67 | KMT2A (0.45) | RECQLKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31548434 | 0.67 | CA1 (0.42) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL19022259 | 0.66 | NPC1 (0.34) | KMT2AMEN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |