Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17543211 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL17542653 | 0.87 | KDM1A (0.37) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL17542883 | 0.86 | KDM1A (0.38) | ALDH1A1L3MBTL1KDM1ALMNAMAPT | |
| SCHEMBL17543284 | 0.84 | LMNA (0.37) | ALDH1A1MEN1KMT2AKDM1APOLB | |
| SCHEMBL17543134 | 0.84 | MAPT (0.38) | ALDH1A1MEN1KMT2AKDM1ALMNA | |
| SCHEMBL28417914 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL17543707 | 0.82 | KDM1A (0.36) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL28413460 | 0.80 | HTR6 (0.37) | ALDH1A1L3MBTL1KDM1ALMNAMAPT | |
| SCHEMBL28418218 | 0.80 | HTR6 (0.37) | ALDH1A1L3MBTL1KDM1ALMNAMAPT | |
| SCHEMBL17543315 | 0.78 | KMT2A (0.40) | ALDH1A1MEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186240-B1 | HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2019-06-12 | — | — | EP | disclosed |