Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17542690 | 0.89 | KCNA5 (0.41) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17542840 | 0.89 | KCNA5 (0.37) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17543517 | 0.85 | MEN1 (0.37) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21048952 | 0.83 | BACE1 (0.36) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17543027 | 0.83 | BACE1 (0.36) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17543058 | 0.83 | BACE1 (0.36) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17543986 | 0.83 | ALDH1A1 (0.38) | KCNA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17542730 | 0.76 | KEAP1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17542731 | 0.76 | KEAP1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17542733 | 0.76 | KEAP1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186240-B1 | HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2019-06-12 | — | — | EP | disclosed |