SCHEMBL21049658

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9558553	0.82	CYP3A4 (0.59)	CYP3A4MEN1MAPTKMT2ATDP1
	SCHEMBL21049655	0.78	GAA (0.58)	MEN1MAPTKMT2AMITFGAA
	SCHEMBL8957487	0.78	MEN1 (0.58)	MEN1MAPTKMT2AMITFGAA
	SCHEMBL9768775	0.77	TDP1 (0.54)	CYP3A4MEN1MAPTKMT2AMITF
	SCHEMBL8058895	0.77	GPR35 (0.69)	CYP3A4MEN1MAPTKMT2AMITF
	SCHEMBL6349986	0.76	CYP3A4 (0.67)	CYP3A4MEN1KMT2ATDP1S100A4
	SCHEMBL21049661	0.74	TSHR (0.51)	CYP3A4TDP1POLBLMNATSHR
	SCHEMBL12192755	0.74	CDK2 (0.56)	CYP3A4MEN1KMT2AS100A4CASP6
	SCHEMBL10701310	0.73	CYP3A4 (0.62)	CYP3A4MEN1MAPTKMT2AGAA
	SCHEMBL5837648	0.72	CYP3A4 (0.57)	CYP3A4MEN1MAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.