Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | ME2 | P23368 | 1/20 | 0.48 |
| ▸ | ME1 | P48163 | 1/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192755 | 0.88 | CDK2 (0.56) | CYP3A4GPR35POLBCDK2CYP2D6 | |
| SCHEMBL5836018 | 0.84 | CYP3A4 (0.59) | CYP3A4GPR35POLBCDK2CYP2D6 | |
| SCHEMBL9827265 | 0.84 | CYP3A4 (0.59) | CYP3A4GPR35POLBCDK2CYP2D6 | |
| SCHEMBL5837648 | 0.83 | CYP3A4 (0.57) | CYP3A4GPR35POLBCDK2CYP2D6 | |
| SCHEMBL21049658 | 0.82 | CYP3A4 (0.53) | CYP3A4GPR35POLBCDK2S100A4 | |
| SCHEMBL6631502 | 0.82 | PTPN1 (0.46) | GPR35POLBCDK2S100A4CASP6 | |
| SCHEMBL6349986 | 0.80 | CYP3A4 (0.67) | CYP3A4GPR35CDK2S100A4CASP6 | |
| SCHEMBL1287816 | 0.80 | WDR5 (0.59) | CYP3A4POLBCDK2S100A4HPGD | |
| SCHEMBL9636835 | 0.80 | CYP3A4 (0.53) | CYP3A4GPR35POLBCDK2CYP2D6 | |
| SCHEMBL3391301 | 0.78 | POLB (0.69) | GPR35POLBCYP2D6CASP6ME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224221-A | Modifier composition for azo pigments based on 2-hydroxy-3-naphthoic acid | AMERICAN CYANAMID COMPANY (US) | 1980-09-23 | — | — | US | claimed |
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | OTSUKA CHEMICAL CO., LTD. (JP) | 2023-07-25 | — | — | US | disclosed |
| CN-109563316-B | Rubber composition, tire, additive and hydrazide compound | 株式会社普利司通 | 2021-08-17 | — | — | CN | disclosed |
| EP-3495415-B1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | BRIDGESTONE CORP (JP) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019156093-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | disclosed |
| WO-2019156094-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | disclosed |
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | BRIDGESTONE CORPORATION (JP) | 2019-06-13 | — | — | US | disclosed |
| EP-3495415-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | Bridgestone Corporation (JP) | 2019-06-12 | — | — | EP | disclosed |
| CN-109563316-A | Rubber composition, tire, additive and hydrazide compound | 株式会社普利司通 | 2019-04-02 | — | — | CN | disclosed |
| US-5201945-A | Mixture of water soluble polysaccharide and organic acid | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-4224221-A | Modifier composition for azo pigments based on 2-hydroxy-3-naphthoic acid | AMERICAN CYANAMID COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | HRH2, HRH1, HEATR1 | CYP3A4 1148/4885GPR35 1021/4885POLB 1393/4885 |
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | HRH2, HRH1, HEATR1 | CYP3A4 1198/4885GPR35 981/4885POLB 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.