SCHEMBL21049945

SCHEMBL21049945

CO[Si](CCCSCCCNC(N)=S)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28651306 0.92 KMT2A (0.35) KMT2APKMHSD17B10LMNAHTT
SCHEMBL6896590 0.86 KMT2A (0.41) KMT2ALMNAALDH1A1GAA
SCHEMBL31213825 0.82 KMT2A (0.39) KMT2ALMNAALDH1A1GAA
Chloroform SCHEMBL28983248 0.79 KMT2A (0.37) KMT2AALDH1A1GAA
SCHEMBL113935 0.78 LMNA (0.39) LMNA
SCHEMBL17225884 0.77 LMNA (0.48) KMT2APKMHSD17B10LMNAHTT
SCHEMBL28992753 0.77 LMNA (0.32) LMNA
SCHEMBL28514761 0.75 CA12 (0.38) KMT2APKMHSD17B10LMNARECQL
SCHEMBL15746700 0.74 PKM (0.33) PKMHSD17B10
SCHEMBL15746699 0.74 PKM (0.33) PKMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12168217-B2 Polyorganic functional groups modified silica, processes to make and use thereof SI-NOVATION LTD (CN) 2024-12-17 US disclosed
CN-117380223-A Rhodium-based catalyst, preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-12 CN disclosed
CN-117380284-A Rhodium-based catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-12 CN disclosed
US-20190176124-A1 POLYORGANIC FUNCTIONAL GROUPS MODIFIED SILICA, PROCESSES TO MAKE AND USE THEREOF SI-NOVATION LTD (CN) 2019-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190176124-A1 POLYORGANIC FUNCTIONAL GROUPS MODIFIED SILICA, PROCESSES TO MAKE AND USE THEREOF STAMBP, TST, AS3MT KMT2A 2551/4885PKM 1361/4885HSD17B10 4754/4885
US-12168217-B2 Polyorganic functional groups modified silica, processes to make and use thereof STAMBP, TST, AS3MT KMT2A 2551/4885PKM 1361/4885HSD17B10 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.