Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716649 | 0.95 | TSHR (0.46) | TSHRFAAHTRPV1 | |
| SCHEMBL6715588 | 0.93 | TSHR (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL6722997 | 0.93 | TSHR (0.42) | TSHRFAAHTRPV1 | |
| SCHEMBL6714009 | 0.91 | L3MBTL1 (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL21925314 | 0.91 | TSHR (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL4630231 | 0.86 | TSHR (0.42) | TSHRTRPV1 | |
| SCHEMBL2094342 | 0.84 | L3MBTL1 (0.41) | TSHR | |
| SCHEMBL8207554 | 0.78 | GNAO1 (0.43) | TSHR | |
| SCHEMBL378009 | 0.75 | — | — | |
| SCHEMBL9325532 | 0.72 | FAAH (0.47) | TSHRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720494-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113375-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2019-06-13 | — | — | WO | disclosed |