Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CD44 | P16070 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569292 | 0.74 | L3MBTL1 (0.62) | KDM4EL3MBTL1ALDH1A1ALOX15TSHR | |
| SCHEMBL29823363 | 0.74 | GRIN2D (0.53) | KDM4EL3MBTL1ALDH1A1ALOX15TSHR | |
| SCHEMBL1874922 | 0.74 | GRIN2D (0.53) | KDM4EL3MBTL1ALDH1A1ALOX15TSHR | |
| SCHEMBL21744699 | 0.72 | TERT (0.46) | CD44CHRM2MAOBPNMT | |
| SCHEMBL29438821 | 0.71 | CHRM2 (0.70) | KDM4EL3MBTL1ALDH1A1ALOX15TSHR | |
| SCHEMBL230222 | 0.71 | CHRM2 (0.70) | KDM4EL3MBTL1ALDH1A1ALOX15TSHR | |
| SCHEMBL25375814 | 0.70 | L3MBTL1 (0.49) | KDM4EL3MBTL1ALDH1A1TSHRCHRM2 | |
| Hydrochloric Acid SCHEMBL5777593 | 0.69 | CD44 (0.46) | CD44MEN1KMT2AHTTMAOB | |
| SCHEMBL14012985 | 0.69 | CD44 (0.53) | CD44MAOBPNMT | |
| SCHEMBL21744250 | 0.69 | CHRM2 (0.52) | KDM4EALDH1A1CHRM2KMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720494-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113375-A2 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Magenta Therapeutics, Inc. (US) | 2019-06-13 | — | — | WO | disclosed |