Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 10/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692079 | 0.92 | ALPL (0.49) | ALPLTRPV4CNR2EPAS1ACLY | |
| SCHEMBL5704864 | 0.80 | TRPV4 (0.62) | ALPLTRPV4CNR2EPAS1AVPR2 | |
| SCHEMBL8075332 | 0.78 | ALPL (0.50) | ALPLCNR2EPAS1ACLYSLC22A12 | |
| Hydrochloric Acid SCHEMBL28145247 | 0.77 | ALPL (0.50) | ALPLCNR2AVPR2GPR27ACLY | |
| SCHEMBL15220356 | 0.76 | SLC22A12 (0.39) | ALPLEPAS1SLC22A12GSTO1 | |
| SCHEMBL29580886 | 0.76 | SLC22A12 (0.39) | ALPLEPAS1SLC22A12GSTO1 | |
| SCHEMBL15211993 | 0.75 | GSTO1 (0.40) | ALPLTRPV4GSTO1 | |
| SCHEMBL4617905 | 0.75 | ALPL (0.48) | ALPLSLC22A12GSTO1 | |
| SCHEMBL6260261 | 0.75 | ALPL (0.56) | ALPLCNR2ACLYSLC22A12 | |
| SCHEMBL10985930 | 0.74 | CNR2 (0.52) | ALPLCNR2EPAS1TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498693-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-06-19 | — | — | EP | disclosed |