SCHEMBL21057641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21057855	0.88	HDAC1 (0.48)	HDAC1HDAC2BRD4HTR2AHTR2C
	SCHEMBL21057930	0.77	TEAD1 (0.36)	HTR2A
	SCHEMBL13432163	0.71	CHRM2 (0.54)	HDAC1HDAC2BRD4HTR2AHTR2C
	SCHEMBL2445835	0.71	HDAC1 (0.46)	HDAC1HDAC2BRD4HTR2AHTR2C
	SCHEMBL27083872	0.71	HDAC1 (0.51)	HDAC1HDAC2BRD4HTR2AHTR2C
	SCHEMBL20476763	0.69	KDM5A (0.52)	HDAC1HDAC2
	SCHEMBL21057768	0.69	HTR2A (0.52)	HDAC1HDAC2HTR2AHTR2CCHRM2
	SCHEMBL20325546	0.69	HDAC1 (0.47)	HDAC1HDAC2BRD4CNR1CNR2
	SCHEMBL12328689	0.69	GRM2 (0.42)	HDAC1HDAC2BRD4HTR2AHTR2C
	SCHEMBL15687430	0.69	HDAC1 (0.47)	HDAC1HDAC2BRD4CNR2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.