SCHEMBL21057930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL411900	0.84	PDE9A (0.38)	SCDHTR2AHTR7KCNH2PDE9A
	SCHEMBL24282885	0.83	POLB (0.42)	TEAD1TEAD4TEAD2SCDHTR2A
	SCHEMBL21058152	0.82	NR3C1 (0.39)	SCDHTR2AHTR7KCNH2PDE9A
	SCHEMBL21060754	0.81	MEN1 (0.43)	SCDHTR2AHTR7KCNH2TNKS
	SCHEMBL25285417	0.80	DDB1 (0.48)	SCDKDM5APDE9ADDB1CRBN
	SCHEMBL21057641	0.77	HDAC1 (0.43)	HTR2A
	SCHEMBL29042016	0.77	SCD (0.37)	TEAD1TEAD4TEAD2SCDHTR2A
	SCHEMBL28439260	0.76	GPR119 (0.38)	SCDHTR2AHTR7KCNH2KDM5A
	SCHEMBL31482830	0.75	PDE9A (0.39)	SCDPDE9A
	SCHEMBL31482815	0.75	KMO (0.40)	TEAD1TEAD4TEAD2SCDKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.