Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608113 | 0.85 | SSTR4 (0.44) | TAAR1ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL21058227 | 0.84 | ATM (0.48) | ALDH1A1NPC1RAB9AHPGDMEN1 | |
| SCHEMBL21058228 | 0.81 | CASR (0.51) | TAAR1ALDH1A1KDM4EBCHEMEN1 | |
| SCHEMBL21105099 | 0.80 | ALDH1A1 (0.43) | TAAR1ALDH1A1ACHEBACE1APP | |
| SCHEMBL21058258 | 0.80 | SIGMAR1 (0.45) | BCHECYP2D6 | |
| SCHEMBL25156570 | 0.79 | HTT (0.49) | TAAR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12201615 | 0.78 | IDO1 (0.50) | TAAR1ALDH1A1ACHEKDM4EHPGD | |
| SCHEMBL8855305 | 0.76 | ALDH1A1 (0.48) | TAAR1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL11876143 | 0.76 | TRPV1 (0.47) | ADRB2BCHEMEN1KMT2ASSTR4 | |
| SCHEMBL11751773 | 0.75 | CYP2D6 (0.48) | TAAR1RAB9AKDM4ECYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | claimed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | claimed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | CHKB, HRH3, PNMT | TAAR1 72/4885ALDH1A1 1501/4885NPC1 3363/4885 |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | CHKB, HRH3, PNMT | TAAR1 86/4885ALDH1A1 1388/4885NPC1 3396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.