SCHEMBL21058349

SCHEMBL21058349

CCCC(=O)N[C@H]1C(O)O[C@H](COP(=O)(Oc2ccccc2)Oc2ccccc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HK1 P19367 10/20 0.44
▸ HK2 P52789 10/20 0.44
▸ AMDHD2 Q9Y303 1/20 0.41
▸ GCK P35557 1/20 0.36
▸ P2RY6 Q15077 3/20 0.36
▸ PYGB P11216 1/20 0.36
▸ P2RY2 P41231 1/20 0.35
▸ P2RY14 Q15391 1/20 0.35
▸ SSTR1 P30872 1/20 0.35
▸ SSTR2 P30874 1/20 0.35
▸ SSTR4 P31391 1/20 0.35
▸ SSTR3 P32745 1/20 0.35
▸ SSTR5 P35346 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28855900 0.85 HK1 (0.46) HK1HK2AMDHD2GCKPYGB
SCHEMBL21137969 0.82 CYP3A4 (0.50) HK1HK2
SCHEMBL21058351 0.80 AMDHD2 (0.62) HK1HK2AMDHD2PYGB
SCHEMBL28503463 0.80 HK1 (0.46) HK1HK2GCKPYGBSSTR1
SCHEMBL7981435 0.79 P2RY14 (0.43) HK1HK2P2RY6P2RY2P2RY14
SCHEMBL21138299 0.78 BTN3A1 (0.45) HK1HK2
SCHEMBL21137962 0.76 AMDHD2 (0.48) AMDHD2P2RY6PYGBP2RY14
SCHEMBL21058343 0.74 HK1 (0.40) HK1HK2PYGBSSTR1SSTR2
SCHEMBL21137950 0.74 AMDHD2 (0.44) HK1HK2AMDHD2PYGB
SCHEMBL26772909 0.73 P2RY14 (0.39) HK1HK2P2RY6P2RY2P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA HK1 83/4885HK2 141/4885AMDHD2 51/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA HK1 111/4885HK2 218/4885AMDHD2 35/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 HK1 72/4885HK2 139/4885AMDHD2 73/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA HK1 111/4885HK2 218/4885AMDHD2 35/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 HK1 463/4885HK2 523/4885AMDHD2 220/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA HK1 83/4885HK2 141/4885AMDHD2 51/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA HK1 83/4885HK2 141/4885AMDHD2 51/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA HK1 83/4885HK2 141/4885AMDHD2 51/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 HK1 72/4885HK2 139/4885AMDHD2 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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