SCHEMBL21058378

SCHEMBL21058378

CCCC(=O)N[C@H]1C(OCc2ccccc2)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ PYGB P11216 1/20 0.48
▸ POLB P06746 1/20 0.47
▸ LGALS8 O00214 1/20 0.46
▸ SSTR1 P30872 1/20 0.46
▸ SSTR2 P30874 1/20 0.46
▸ SSTR4 P31391 1/20 0.46
▸ SSTR3 P32745 1/20 0.46
▸ SSTR5 P35346 1/20 0.46
▸ SLC6A2 P23975 1/20 0.44
▸ HRAS P01112 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958752 0.92 MAPK1 (0.55) CA1CA2CA9MAPK1SSTR3
SCHEMBL10958757 0.92 MAPK1 (0.55) CA1CA2CA9MAPK1SSTR3
SCHEMBL21058364 0.92 SSTR3 (0.55) LGALS8SSTR1SSTR2SSTR4SSTR3
SCHEMBL25835254 0.91 CA1 (0.48) CA1CA2CA9MAPK1PYGB
SCHEMBL8652701 0.90 SLC6A2 (0.48) CA1CA2CA9POLBLGALS8
SCHEMBL21058342 0.87 SSTR3 (0.48) LGALS8SSTR1SSTR2SSTR4SSTR3
SCHEMBL21097246 0.86 MAPK1 (0.58) MAPK1POLBHRAS
SCHEMBL542627 0.86 MAPK1 (0.58) MAPK1POLBHRAS
SCHEMBL5841792 0.86 MAPK1 (0.58) MAPK1POLBHRAS
SCHEMBL7150940 0.86 MAPK1 (0.58) MAPK1POLBHRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
CN-115215911-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2024-07-05 — — CN disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
CN-115594724-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司(CN) 2023-01-13 — — CN disclosed
CN-115215911-A Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-10-21 — — CN disclosed
CN-111971290-B Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2022-10-14 — — CN disclosed
CN-109929001-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-07-08 — — CN disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
CN-111971290-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2020-11-20 — — CN disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA CA1 3238/4885CA2 3597/4885CA9 1737/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA CA1 3104/4885CA2 4331/4885CA9 2393/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 CA1 3867/4885CA2 4317/4885CA9 2820/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA CA1 3104/4885CA2 4331/4885CA9 2393/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 CA1 3919/4885CA2 3152/4885CA9 3422/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA CA1 3238/4885CA2 3597/4885CA9 1737/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA CA1 3238/4885CA2 3597/4885CA9 1737/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA CA1 3238/4885CA2 3597/4885CA9 1737/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 CA1 3867/4885CA2 4317/4885CA9 2820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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