Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 15/20 | 0.61 |
| ▸ | GSTA1 | P08263 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.61 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.61 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260755 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22260748 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22260650 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL21062155 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL21062156 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22260753 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22260750 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22260738 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22485842 | 1.00 | GSTP1 (0.61) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22486536 | 0.96 | GSTP1 (0.57) | GSTP1GSTA1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058971-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230056284-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-11160870-B2 | Extended release microparticles and suspensions thereof for medical therapy | Graybug Vision, Inc. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210275456-A1 | AGGREGATED MICROPARTICLES | Graybug Vision, Inc. (US) | 2021-09-09 | — | — | US | disclosed |
| EP-3723750-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| US-20200308162-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2020-10-01 | — | — | US | disclosed |
| US-20200308162-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2020-10-01 | — | — | US | disclosed |
| CN-111465394-A | Drugs and compositions for ocular delivery | 灰色视觉公司 | 2020-07-28 | — | — | CN | disclosed |
| US-20200230246-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | Graybug Vision, Inc. (US) | 2020-07-23 | — | — | US | disclosed |
| WO-2019118924-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308162-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | AGER, PDE6B, PTGER1 | GSTP1 834/4885GSTA1 770/4885MEN1 790/4885 |
| US-11160870-B2 | Extended release microparticles and suspensions thereof for medical therapy | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20230058971-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20200230246-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
| US-20210275456-A1 | AGGREGATED MICROPARTICLES | VCL, MYOC, CD44 | GSTP1 3715/4885GSTA1 3135/4885MEN1 1158/4885 |
| US-20230056284-A1 | EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY | CHMP4B, EXOSC9, EXOSC5 | GSTP1 4578/4885GSTA1 4632/4885MEN1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.