⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279979 | 0.88 | KMT2A (0.42) | — | |
| SCHEMBL16116449 | 0.81 | — | — | |
| SCHEMBL3128954 | 0.77 | POLB (0.38) | — | |
| SCHEMBL8862946 | 0.73 | CHRM2 (0.41) | — | |
| SCHEMBL8863095 | 0.73 | POLB (0.43) | — | |
| SCHEMBL4390120 | 0.73 | MEN1 (0.44) | — | |
| SCHEMBL10807717 | 0.71 | — | — | |
| SCHEMBL10973154 | 0.71 | FAAH (0.46) | — | |
| SCHEMBL9031379 | 0.69 | CHRM2 (0.59) | — | |
| SCHEMBL13907969 | 0.69 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | disclosed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | disclosed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| EP-2465842-A1 | Amines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| US-8157950-B2 | Aldimine and composition containing aldimine | SIKA TECHNOLOGY AG (CH) | 2012-04-17 | — | — | US | disclosed |
| US-20110253309-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-10-20 | — | — | US | disclosed |
| EP-2194082-B1 | Aldimine and composition comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010063741-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| US-4412999-A | Anti-emetic esters of cyproheptadine-3-carboxylic acid and structurally related compounds | MERCK & CO., INC. (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0092114-A2 | Esters of cyproheptadine-3-carboxylic acid and structurally related compounds, process for their preparation and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1983-10-26 | — | — | EP | disclosed |
| US-4198413-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4143146-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4058530-A | PHENYLALANINE, ANTIHYPERTENSIVE | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4051169-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4038411-A | ANTIHYPERTENSIVE AMINO ACID ESTERS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3988341-A | Esterification process | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3983138-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1976-09-28 | — | — | US | disclosed |