Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220928 | 0.92 | USP30 (0.43) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| SCHEMBL25093627 | 0.88 | DDB1 (0.58) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| SCHEMBL21063452 | 0.87 | GPR119 (0.52) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| SCHEMBL29220893 | 0.86 | USP30 (0.49) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| Lithium Ion SCHEMBL21063388 | 0.84 | DDB1 (0.44) | USP30DDB1CRBNKMT2ASMN1; SMN2 | |
| SCHEMBL25093965 | 0.84 | PARP1 (0.48) | USP30KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL31178523 | 0.84 | PARP1 (0.48) | USP30KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL30394540 | 0.83 | DDB1 (0.46) | DDB1CRBNKMT2AMEN1MAPT | |
| SCHEMBL255458 | 0.83 | DDB1 (0.46) | DDB1CRBNKMT2AMEN1MAPT | |
| SCHEMBL25215675 | 0.81 | USP30 (0.49) | USP30DDB1CRBNKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119629-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-31 | — | — | CN | disclosed |