SCHEMBL21063530

SCHEMBL21063530

N#CCCC1CN(C(=O)O)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1772783 0.81 ITGB3 (0.36) MEN1KMT2A
SCHEMBL14697421 0.79
SCHEMBL14738055 0.74 AKR1C3 (0.41)
SCHEMBL2004619 0.72 ARG1 (0.35)
SCHEMBL14737804 0.72
SCHEMBL19437244 0.72 PDK1 (0.38)
SCHEMBL21068655 0.71 NAMPT (0.33)
SCHEMBL19439263 0.71
SCHEMBL1772248 0.71 ITGB3 (0.40)
SCHEMBL12561500 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531695-B JAK inhibitors 无锡福祈制药有限公司 2020-03-27 CN disclosed
WO-2019118612-A1 TARGETING COMPOUNDS ZAFGEN, INC. (US) 2019-06-20 WO disclosed