Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 4/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21063623 | 0.91 | KDM2B (0.40) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL16268981 | 0.84 | KDM5A (0.44) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL13406413 | 0.83 | KDM2B (0.49) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL12985681 | 0.81 | CDK5 (0.48) | KDM2BKDM5ACDK5CDK5R1CPB1 | |
| SCHEMBL2331925 | 0.81 | CPB2 (0.45) | KDM2BKDM5AKDM4ECDK5CDK5R1 | |
| SCHEMBL28070514 | 0.79 | CPB2 (0.44) | KDM2BKDM5AKDM4ECDK5CDK5R1 | |
| Hydrochloric Acid SCHEMBL12985270 | 0.79 | CDK5 (0.47) | KDM2BKDM5ACDK5CDK5R1CPB1 | |
| SCHEMBL2327699 | 0.79 | CPB2 (0.47) | KDM2BKDM5AKDM4ECDK5CDK5R1 | |
| SCHEMBL21098465 | 0.78 | KDM5A (0.41) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL2330015 | 0.77 | GSK3B (0.43) | KDM2BKDM5AKDM4AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |