Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063598 | 0.91 | KDM2B (0.45) | KDM2BCHRNA7KDM5AKDM4AKDM4C | |
| SCHEMBL21063624 | 0.80 | KDM2B (0.33) | KDM2BKDM5A | |
| SCHEMBL16268981 | 0.76 | KDM5A (0.44) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL13406413 | 0.76 | KDM2B (0.49) | KDM2BKDM5AKDM4AKDM4CKDM5B | |
| SCHEMBL12985681 | 0.73 | CDK5 (0.48) | KDM2BKDM5A | |
| SCHEMBL2331925 | 0.73 | CPB2 (0.45) | KDM2BKDM5AKDM4E | |
| SCHEMBL2327699 | 0.72 | CPB2 (0.47) | KDM2BKDM5AKDM4E | |
| Hydrochloric Acid SCHEMBL12985270 | 0.72 | CDK5 (0.47) | KDM2BKDM5A | |
| SCHEMBL28070514 | 0.72 | CPB2 (0.44) | KDM2BKDM5AKDM4E | |
| Trifluoroacetic Acid SCHEMBL21063578 | 0.71 | CHRNA7 (0.38) | CHRNA7IRAK4CHRNB2CHRNA4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |