Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767119 | 0.82 | SIGMAR1 (0.33) | LMNAGAA | |
| SCHEMBL11776669 | 0.79 | — | — | |
| SCHEMBL16767596 | 0.79 | SIGMAR1 (0.32) | LMNAGAA | |
| SCHEMBL16767287 | 0.76 | SIGMAR1 (0.38) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL12445307 | 0.72 | LMNA (0.40) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL1326671 | 0.68 | LMNA (0.38) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL24577788 | 0.67 | POLB (0.38) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL30984513 | 0.67 | LMNA (0.37) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL545962 | 0.66 | ADRA1A (0.39) | LMNAGAAADRA1DADRA1AADRA1B | |
| SCHEMBL19521305 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290599-B2 | Functionalized polymers and tires therefrom | BRIDGESTONE CORPORATION (JP) | 2016-03-22 | — | — | US | disclosed |
| US-8618223-B2 | Functionalized polymers and tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-12-31 | — | — | US | disclosed |
| US-20120180937-A1 | FUNCTIONALIZED POLYMERS AND TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| US-8158725-B2 | Functionalized polymers and tires therefrom | BRIDGESTONE CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20070055024-A1 | Functionalized polymers and tires therefrom | BRIDGESTONE CORPORATION (JP) | 2007-03-08 | — | — | US | disclosed |