Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848037 | 1.00 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL29758993 | 0.96 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6383024 | 0.92 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL3003480 | 0.89 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11265164 | 0.87 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL6682956 | 0.87 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL16909193 | 0.87 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL375061 | 0.86 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL15454179 | 0.86 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL29885718 | 0.86 | ALDH1A1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617687-B2 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | MEDIBEACON INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-RE47413-E1 | Pyrazine derivatives and uses thereof in renal monitoring | MEDIBEACON, INC. (US) | 2019-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617687-B2 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | GLS, CYP4F12, XDH | ALDH1A1 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.