Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652076 | 0.90 | PRMT1 (0.39) | PRMT1MAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28657004 | 0.80 | PRMT1 (0.40) | PRMT1MAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7760598 | 0.72 | TSHR (0.51) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL7766271 | 0.72 | TSHR (0.51) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL27561962 | 0.71 | MAPT (0.39) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL8651106 | 0.71 | ATR (0.47) | MAPTMEN1ALDH1A1KMT2AATR | |
| SCHEMBL27637022 | 0.69 | CA12 (0.40) | PRMT1MAPTMEN1KMT2AMMP1 | |
| SCHEMBL30290973 | 0.68 | KCNA5 (0.47) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3576370 | 0.67 | ALDH1A1 (0.46) | PRMT1MAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7196335 | 0.67 | MAPT (0.51) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083582-B1 | A NEW PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL | FARMA GRS D O O (SI) | 2019-06-26 | — | — | EP | claimed |