Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316956 | 0.90 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27749588 | 0.88 | ALDH1A1 (0.67) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5059081 | 0.88 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL21065601 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1DHODH | |
| SCHEMBL28458575 | 0.85 | ALDH1A1 (0.63) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6718454 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6340266 | 0.84 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL21065619 | 0.84 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Methacrylic Acid SCHEMBL7262504 | 0.83 | ALDH1A1 (0.61) | MAPTALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL1172378 | 0.83 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115298573-A | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | claimed |
| CN-106999629-B | Low water content acrylate-acrylamide copolymers for ophthalmic devices | 诺华股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116888193-A | Polysiloxane vinyl cross-linking agent with high refractive index | 爱尔康公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115698776-A | Insert material with high oxygen permeability coefficient and high refractive index | 爱尔康公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111712523-B | Ophthalmic product composition | 爱尔兰眼力健公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115298574-A | Embedded silicone hydrogel contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115298573-A | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| CN-111712523-A | Ophthalmic product composition | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-106999629-B | Low water content acrylate-acrylamide copolymers for ophthalmic devices | 诺华股份有限公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |