SCHEMBL21065619

SCHEMBL21065619

C=C(C(=O)OCC)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.50
PLA2G10 O15496 1/20 0.49
PLA2G2A P14555 1/20 0.49
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LTA4H P09960 9/20 0.45
SRD5A2 P31213 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27759952 0.88 LMNA (0.50) ALDH1A1MAPTLMNASMN1; SMN2PLA2G10
SCHEMBL316956 0.87 ALDH1A1 (0.69) ALDH1A1MAPTLMNASMN1; SMN2MEN1
Ammonia Solution, Strong SCHEMBL27749588 0.85 ALDH1A1 (0.67) ALDH1A1MAPTLMNASMN1; SMN2MEN1
SCHEMBL5059081 0.85 MAPT (0.55) ALDH1A1MAPTLMNASMN1; SMN2MEN1
SCHEMBL21636278 0.84 ALDH1A1 (0.57) ALDH1A1MAPTLMNASMN1; SMN2PLA2G10
SCHEMBL21065617 0.84 MAPT (0.57) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
Diphenylmethane SCHEMBL26922258 0.83 ALDH1A1 (0.56) ALDH1A1MAPTLMNASMN1; SMN2MEN1
SCHEMBL28458575 0.82 ALDH1A1 (0.63) ALDH1A1MAPTLMNASMN1; SMN2MEN1
SCHEMBL6718454 0.82 ALDH1A1 (0.53) ALDH1A1MAPTLMNASMN1; SMN2MEN1
SCHEMBL6340266 0.81 ALDH1A1 (0.54) ALDH1A1MAPTLMNASMN1; SMN2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN claimed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN disclosed
CN-116888193-A Polysiloxane vinyl cross-linking agent with high refractive index 爱尔康公司 2023-10-13 CN disclosed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN disclosed
CN-111712523-B Ophthalmic product composition 爱尔兰眼力健公司 2023-01-03 CN disclosed
CN-115298574-A Embedded silicone hydrogel contact lenses 爱尔康公司 2022-11-04 CN disclosed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN disclosed
EP-3728339-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2020-10-28 EP disclosed
CN-111712523-A Ophthalmic product composition 默克专利股份有限公司 2020-09-25 CN disclosed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN disclosed
EP-3502147-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2019-06-26 EP disclosed