Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947935 | 1.00 | ESR1 (0.46) | ESR1ESR2PDE3BPDE3AMEN1 | |
| SCHEMBL11218403 | 0.82 | ALDH1A1 (0.42) | PDE3BPDE3AMEN1KMT2ANPC1 | |
| SCHEMBL11227322 | 0.82 | KMT2A (0.42) | MEN1KMT2AMAPTSMN1; SMN2CCNB2 | |
| SCHEMBL11680776 | 0.82 | MAPT (0.42) | PDE3BPDE3AMEN1KMT2ARAB9A | |
| SCHEMBL8895956 | 0.81 | SLC22A12 (0.43) | PDE3BPDE3AMEN1KMT2AMAPT | |
| SCHEMBL11219648 | 0.77 | KDM4E (0.64) | ESR2PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL11216382 | 0.74 | IDO1 (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11947288 | 0.73 | CCNB2 (0.39) | ESR1ESR2PDE3BPDE3AMEN1 | |
| SCHEMBL2475792 | 0.73 | MMP3 (0.45) | ESR1ESR2PDE3BPDE3AMEN1 | |
| SCHEMBL3720609 | 0.71 | PTGS2 (0.51) | ESR1ESR2MEN1KMT2ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112305117-B | Chromatographic detection method for determining related substances of amoxicillin and clavulanate potassium | 四川制药制剂有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-112305117-B | Chromatographic detection method for determining related substances of amoxicillin and clavulanate potassium | 四川制药制剂有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-112305117-A | Chromatographic detection method for determining related substances of amoxicillin and clavulanate potassium | 四川制药制剂有限公司 | 2021-02-02 | — | — | CN | disclosed |
| EP-3501476-A1 | DRUG DELIVERY DEVICE FOR PHARMACEUTICAL COMPOSITIONS | Sun Pharmaceutical Industries Limited (IN) | 2019-06-26 | — | — | EP | disclosed |