SCHEMBL21066

SCHEMBL21066

OCCC1CCC(F)(F)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.39
ESR2 Q92731 2/20 0.35
NAAA Q02083 1/20 0.34
ASAH1 Q13510 1/20 0.34
FFAR4 Q5NUL3 1/20 0.32
P2RX7 Q99572 2/20 0.32
IL1B P01584 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18091610 0.86 NAAA (0.38) APLNRNAAAASAH1
SCHEMBL12206360 0.86 APLNR (0.46) APLNR
SCHEMBL16056471 0.84 NAAA (0.40) APLNRNAAAASAH1
SCHEMBL22907 0.79 APLNR (0.55) APLNRESR2
SCHEMBL30885140 0.77 NAAA (0.35) NAAAASAH1
SCHEMBL21065 0.75 NAAA (0.34) NAAAASAH1
SCHEMBL178385 0.75 CYP1A2 (0.36) NAAAASAH1
SCHEMBL16910853 0.75 NAAA (0.34) NAAAASAH1
SCHEMBL6484450 0.75 ESR2 (0.35) ESR2
SCHEMBL19555539 0.75 CHRM2 (0.37) NAAAASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 US disclosed
US-9040457-B2 Phenylamidines having a high fungicidal activity and use thereof ISAGRO S.P.A. (IT) 2015-05-26 US disclosed
WO-2013149124-A1 SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2013-10-03 WO disclosed
EP-2608666-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF ISAGRO S.p.A. (IT) 2013-07-03 EP disclosed
US-20130157851-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF ISAGRO S.P.A. (IT) 2013-06-20 US disclosed
WO-2012025450-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF ISAGRO RICERCA S.R.L. (IT) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130157851-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF PAH, DPM1, PFAS APLNR 4657/4885ESR2 4554/4885NAAA 278/4885
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 APLNR 3537/4885ESR2 2913/4885NAAA 4844/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS APLNR 3658/4885ESR2 1462/4885NAAA 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.